Important Safety Information
QVAR® is not a bronchodilator and is not indicated for relief of acute bronchospasm. Common side effects associated with the use of QVAR® and placebo in clinical trials include, but are not limited to, headache (12% and 9%, respectively) and pharyngitis (8% and 4%, respectively). Caution: Adrenal insufficiency may occur when transferring patients from systemic steroids (see WARNINGS, Prescribing Information). A reduction in growth velocity in growing children and teenagers may occur as a result of inadequate control of chronic diseases such as asthma or from use of corticosteroids for treatment.
Teva's Safe Harbor Statement under the U. S. Private Securities Litigation Reform Act of 1995: This release contains forward-looking statements, which express the current beliefs and expectations of management. Such statements are based on management's current beliefs and expectations and involve a number of known and unknown risks and uncertainties that could cause our future results, performance or achievements to differ significantly from the results, performance or achievements expressed or implied by such forward-looking statements. Important factors that could cause or contribute to such differences include risks relating to: our ability to successfully develop and commercialize additional pharmaceutical products, the introduction of competing generic equivalents, the extent to which we may obtain U.S. market exclusivity for certain of our new generic products and regulatory changes that may prevent us from utilizing exclusivity periods, potential liability for sales of generic products prior to a final resolution of outstanding patent litigation, including that relating to the generic versions of Neurontin®, Lotrel® and Protonix®, the extent to which any manufacturing or quality control problems damage our reputation for high quality production, the effects of competition on sales of our innovative products, especially Copaxone® (including potential generic and oral competition for Copaxone®), the impact of continuing consolidation of our distributors and customers, our ability to identify, consummate and successfully integrate acquisitions, interruptions in our supply chain or problems with our information technology systems that adversely affect our complex manufacturing processes, intense competition in our specialty pharmaceutical businesses, any failures to comply with the complex Medicare and Medicaid reporting and payment obligations, our exposure to currency fluctuations and restrictions as well as credit risks, the effects of reforms in healthcare regulation, adverse effects of political or economical instability, major hostilities or acts of terrorism on our significant worldwide operations, increased government scrutiny in both the U.S. and Europe of our agreements with brand companies, dependence on the effectiveness of our patents and other protections for innovative products, our ability to achieve expected results through our innovative R&D efforts, the difficulty of predicting U.S. Food and Drug Administration, European Medicines Agency and other regulatory authority approvals, uncertainties surrounding the legislative and regulatory pathway for the registration and approval of biotechnology-based products, potentially significant impairments of intangible assets and goodwill, potential increases in tax liabilities resulting from challenges to our intercompany arrangements, our potential exposure to product liability claims to the extent not covered by insurance, the termination or expiration of governmental programs or tax benefits, current economic conditions, any failure to retain key personnel or to attract additional executive and managerial talent, environmental risks and other factors that are discussed in this report and in our other filings with the U.S. Securities and Exchange Commission ("SEC").
Sunday, August 22, 2010
Wednesday, June 9, 2010
Our Body Work as a Team?
What Does "Tissue" Mean, and Do the Tissues Throughout Our
Body Work as a Team?
Humans are truly a complex array of organs and other tissues designed
to support the basic functions and vitality of our body. We are able to
process inhaled air and ingested food and regulate body content. We
selectively take what we need from the external environment and elimin-
ate what we do not need. We think, move about, and reproduce. Many of
these operations occur without us even being aware of them.
One other term we should be familiar with is tissue. Quite
simply, tissue is composed of similar or cooperating cells performing
similar or cooperative tasks. These cells may be grouped together to form
fascinating tissues such as bone, skin, muscle, nerves, and blood.
Body Work as a Team?
Humans are truly a complex array of organs and other tissues designed
to support the basic functions and vitality of our body. We are able to
process inhaled air and ingested food and regulate body content. We
selectively take what we need from the external environment and elimin-
ate what we do not need. We think, move about, and reproduce. Many of
these operations occur without us even being aware of them.
One other term we should be familiar with is tissue. Quite
simply, tissue is composed of similar or cooperating cells performing
similar or cooperative tasks. These cells may be grouped together to form
fascinating tissues such as bone, skin, muscle, nerves, and blood.
Tuesday, June 8, 2010
Extracellular Fluids?
What Types of Substances Are Found in the Intracellular and
Extracellular Fluids?
In our body fluids we would find small dissolved substances such as ions,
amino acids, and the carbohydrate glucose, as well as larger proteins. The
major ions (or electrolytes) would include potassium (K+), sodium
(Na+), chloride (Cl−), calcium (Ca2+), magnesium (Mg2+), phosphate
(PO43−), and bicarbonate (HCO3−). As demonstrated in Figure 2.2, all of
these and other substances will be found in both the intracellular and
extracellular fluids. However, the concentration of substances dissolved
in either fluid varies and the plasma membrane is bestowed with the
awesome responsibility of functioning as a barrier between the two
mediums.
Extracellular Fluids?
In our body fluids we would find small dissolved substances such as ions,
amino acids, and the carbohydrate glucose, as well as larger proteins. The
major ions (or electrolytes) would include potassium (K+), sodium
(Na+), chloride (Cl−), calcium (Ca2+), magnesium (Mg2+), phosphate
(PO43−), and bicarbonate (HCO3−). As demonstrated in Figure 2.2, all of
these and other substances will be found in both the intracellular and
extracellular fluids. However, the concentration of substances dissolved
in either fluid varies and the plasma membrane is bestowed with the
awesome responsibility of functioning as a barrier between the two
mediums.
Sunday, June 6, 2010
Free radicals are molecules
The presence of free radicals in our body is not necessarily a disease and
seems to be unavoidable. That's because free radicals are normally pro-
duced when we breakdown carbohydrates, protein, and fat for energy.
Furthermore, certain immune processes purposely generate free-radical
substances to attack foreign entities or debris in our body. However, free
radicals can certainly lead to disease if their presence becomes too great
and they are left to their own devices. This tends to happen when we
allow free radicals access to our body via the foods we eat and the
substances we breathe. Cigarette smoke is loaded with free-radical sub-
stances, probably more than one hundred different kinds.
Free radicals are molecules that can take electrons from other
molecules thereby causing damage.
seems to be unavoidable. That's because free radicals are normally pro-
duced when we breakdown carbohydrates, protein, and fat for energy.
Furthermore, certain immune processes purposely generate free-radical
substances to attack foreign entities or debris in our body. However, free
radicals can certainly lead to disease if their presence becomes too great
and they are left to their own devices. This tends to happen when we
allow free radicals access to our body via the foods we eat and the
substances we breathe. Cigarette smoke is loaded with free-radical sub-
stances, probably more than one hundred different kinds.
Free radicals are molecules that can take electrons from other
molecules thereby causing damage.
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Wednesday, May 19, 2010
Benefits of exercising
Benefits of exercising
• Boost to your emotional well being – Even light exercise can help boost your
mood. Also, more intense exercise can stimulate the release of mood elevating
compounds called endorphins.
• Reduce risk of heart disease – If you are overweight or obese, you are more
prone to heart disease, as you have a higher risk of cardiovascular disease. You
can improve your cardiovascular function if you partake in exercise.
• Improvement to memory – If you exercise more regularly, you move blood
and oxygen to all your body's organs, including the brain, which is great for
revitalising your mind.
• Reduced risk of Diabetes – Physically active people are less likely to develop
Diabetes, as exercise increases the body's ability to use sugar for energy and
thereby decreases the need for insulin.
• Other benefits include: - Improved sleep pattern, increased strength,
improved energy level, pain relief, longevity and increased bone density.
• Boost to your emotional well being – Even light exercise can help boost your
mood. Also, more intense exercise can stimulate the release of mood elevating
compounds called endorphins.
• Reduce risk of heart disease – If you are overweight or obese, you are more
prone to heart disease, as you have a higher risk of cardiovascular disease. You
can improve your cardiovascular function if you partake in exercise.
• Improvement to memory – If you exercise more regularly, you move blood
and oxygen to all your body's organs, including the brain, which is great for
revitalising your mind.
• Reduced risk of Diabetes – Physically active people are less likely to develop
Diabetes, as exercise increases the body's ability to use sugar for energy and
thereby decreases the need for insulin.
• Other benefits include: - Improved sleep pattern, increased strength,
improved energy level, pain relief, longevity and increased bone density.
Sunday, March 14, 2010
40 million Americans have difficulty sleeping
Insomnia
More than 40 million Americans have difficulty sleeping, but only an estimated 5 million people live with fibromyalgia—which means there are plenty of reasons why you may not be getting a good night’s sleep. Learn about some of the more common sleep disorders in Health.com’s comprehensive sleep resource center.
If you suffer from serious fatigue that limits your daily activities, accompanied by difficulties with concentration and memory, and chronic pain, you have the three most significant symptoms of fibromyalgia. “These three group together,” says Dr. Clauw. “If you have all three, it’s likely you have fibro.” Still, he cautions that the type of pain you have is the single most important predictor of whether you have fibromyalgia.
related
SleepWell
Buspar
Anexil
REM Again
More than 40 million Americans have difficulty sleeping, but only an estimated 5 million people live with fibromyalgia—which means there are plenty of reasons why you may not be getting a good night’s sleep. Learn about some of the more common sleep disorders in Health.com’s comprehensive sleep resource center.
If you suffer from serious fatigue that limits your daily activities, accompanied by difficulties with concentration and memory, and chronic pain, you have the three most significant symptoms of fibromyalgia. “These three group together,” says Dr. Clauw. “If you have all three, it’s likely you have fibro.” Still, he cautions that the type of pain you have is the single most important predictor of whether you have fibromyalgia.
related
SleepWell
Buspar
Anexil
REM Again
Chronic bladder pain may play in fibromyalgia
Bladder pain
Experts are increasingly recognizing the role that chronic bladder pain may play in fibromyalgia. “It’s a new focus [in pain research],” says Dr. Clauw. “It’s basically the irritable bowel syndrome of the bladder.” Symptoms include pain in the bladder or pelvic region accompanied by feeling the need to urinate frequently.
If these symptoms are short-lived, the most likely culprit is an easily treated bladder or urinary tract infection. Or, if the only symptom is the urge to urinate, the condition is called overactive bladder syndrome.
When combined with all-over chronic pain, bladder pain may be a component of fibromyalgia. Though currently called interstitial cystitis, Dr. Clauw says the name is rapidly changing to “painful bladder syndrome,” which more accurately describes it.
Experts are increasingly recognizing the role that chronic bladder pain may play in fibromyalgia. “It’s a new focus [in pain research],” says Dr. Clauw. “It’s basically the irritable bowel syndrome of the bladder.” Symptoms include pain in the bladder or pelvic region accompanied by feeling the need to urinate frequently.
If these symptoms are short-lived, the most likely culprit is an easily treated bladder or urinary tract infection. Or, if the only symptom is the urge to urinate, the condition is called overactive bladder syndrome.
When combined with all-over chronic pain, bladder pain may be a component of fibromyalgia. Though currently called interstitial cystitis, Dr. Clauw says the name is rapidly changing to “painful bladder syndrome,” which more accurately describes it.
Common symptom of fibromyalgia
Upset stomach
Irritable Bowel Syndrome (IBS), which is characterized by stomach cramping, bloating, and diarrhea or constipation, is a common symptom of fibromyalgia. But many people have the condition on its own.
IBS can be triggered by stress, hormonal changes, certain foods, or even antibiotics, and it can be treated with diet and lifestyle changes and with medication. If you have chronic abdominal discomfort with diarrhea or constipation accompanied by the pain described in the previous slide, it’s worth asking your doctor if you might be suffering from fibromyalgia.
Irritable Bowel Syndrome (IBS), which is characterized by stomach cramping, bloating, and diarrhea or constipation, is a common symptom of fibromyalgia. But many people have the condition on its own.
IBS can be triggered by stress, hormonal changes, certain foods, or even antibiotics, and it can be treated with diet and lifestyle changes and with medication. If you have chronic abdominal discomfort with diarrhea or constipation accompanied by the pain described in the previous slide, it’s worth asking your doctor if you might be suffering from fibromyalgia.
One symptom of fibromyalgia
All-over pain
The number-one symptom of fibromyalgia is persistent pain all over your body in your muscles and joints for an extended period of time. "[If a patient says,] 'I hurt all over,'" says rheumatologist Daniel Clauw, MD, director of the Chronic Pain and Fatigue Research Center at the University of Michigan, "that’s a big blinking neon light that it’s fibro." Rebecca, who has lived with fibromyalgia for more than three decades, says it feels like a bruise that covers your entire body.
Other conditions, such as lupus and rheumatoid arthritis, can initially cause a feeling of widespread pain. “If it’s just in the joints, that person really should see a rheumatologist or someone who specializes in rheumatic or musculoskeletal disorders to make sure they don’t have arthritis,” says Dr. Clauw. Chronic pain that is exclusively in the muscles, on the other hand, can sometimes be polymyalgia rheumatica. But any pain that persists for years in both the muscles and the joints, Clauw explains, is most likely fibro.
The number-one symptom of fibromyalgia is persistent pain all over your body in your muscles and joints for an extended period of time. "[If a patient says,] 'I hurt all over,'" says rheumatologist Daniel Clauw, MD, director of the Chronic Pain and Fatigue Research Center at the University of Michigan, "that’s a big blinking neon light that it’s fibro." Rebecca, who has lived with fibromyalgia for more than three decades, says it feels like a bruise that covers your entire body.
Other conditions, such as lupus and rheumatoid arthritis, can initially cause a feeling of widespread pain. “If it’s just in the joints, that person really should see a rheumatologist or someone who specializes in rheumatic or musculoskeletal disorders to make sure they don’t have arthritis,” says Dr. Clauw. Chronic pain that is exclusively in the muscles, on the other hand, can sometimes be polymyalgia rheumatica. But any pain that persists for years in both the muscles and the joints, Clauw explains, is most likely fibro.
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